Abemaciclib

Product Specifications

CAS Number

1231929-97-7

Target

CDK

Related Pathways

Cell Cycle/Checkpoint

Purity

0.9987

Bioactivity

Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity. Abemaciclib has antitumor activity and is used to treat advanced or metastatic breast cancer.

Smiles

C(C)(C)N1C=2C(=C(F)C=C(C2)C3=NC(NC4=CC=C(CN5CCN(CC)CC5)C=N4)=NC=C3F)N=C1C

Molecular Formula

C27H32F2N8

Molecular Weight

506.59

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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