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BMS-986169

Product Specifications

CAS Number

1801151-08-5

Target

Others|||NMDAR|||iGluR

Related Pathways

Neuroscience|||Membrane transporter/Ion channel|||Others

Purity

0.9761

Bioactivity

BMS-986169 is a high-affinity and selective negative allosteric modulator of the NMDA receptor GluN2B subunit, with an IC50 of 24 nM in oocytes, and exhibits antidepressant-like activity in mice, making it a potential treatment for treatment-resistant depression.

Smiles

O=C1[C@@H](CCN1CC2=CC=C(C)C=C2)N3C[C@@H](F)[C@@H](CC3)C4=CC=C(O)C=C4

Molecular Formula

C23H27FN2O2

Molecular Weight

382.47

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/F0D6F9E6-5B53-4272-8C92-61377D294D69/T23808

Available Sizes

Curated Selection

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