BMS-986169
Product Specifications
CAS Number
1801151-08-5
Target
Others|||NMDAR|||iGluR
Related Pathways
Neuroscience|||Membrane transporter/Ion channel|||Others
Purity
0.9761
Bioactivity
BMS-986169 is a high-affinity and selective negative allosteric modulator of the NMDA receptor GluN2B subunit, with an IC50 of 24 nM in oocytes, and exhibits antidepressant-like activity in mice, making it a potential treatment for treatment-resistant depression.
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O=C1[C@@H](CCN1CC2=CC=C(C)C=C2)N3C[C@@H](F)[C@@H](CC3)C4=CC=C(O)C=C4
Molecular Formula
C23H27FN2O2
Molecular Weight
382.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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