BIRT-377
Product Specifications
CAS Number
213211-10-0
Target
Integrin, IL Receptor, Interleukin
Related Pathways
Immunology/Inflammation, Cytoskeletal Signaling
Purity
>99.99%
Bioactivity
BIRT-377 is a negative allosteric and orally bioavailable inhibitor of ICAM-1 and LFA-1 (Ki = 25.8 nM) . BIRT-377 inhibits the production of IL-2 and can be used in studies about inflammatory and immune disorders.
Smiles
CN1C(=O)N(C(=O)[C@@]1(C)Cc1ccc(Br)cc1)c1cc(Cl)cc(Cl)c1
Molecular Formula
C18H15BrCl2N2O2
Molecular Weight
442.13
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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