BIRT-377

Product Specifications

CAS Number

213211-10-0

Target

Integrin|||IL Receptor|||Interleukin

Related Pathways

Immunology/Inflammation|||Cytoskeletal Signaling

Purity

>99.99%

Bioactivity

BIRT-377 is a negative allosteric and orally bioavailable inhibitor of ICAM-1 and LFA-1 (Ki = 25.8 nM) . BIRT-377 inhibits the production of IL-2 and can be used in studies about inflammatory and immune disorders.

Smiles

CN1C(=O)N(C(=O)[C@@]1(C)Cc1ccc(Br)cc1)c1cc(Cl)cc(Cl)c1

Molecular Formula

C18H15BrCl2N2O2

Molecular Weight

442.13

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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