Ponatinib Hydrochloride
Product Specifications
CAS Number
1114544-31-8
Target
PDGFR, Autophagy, FGFR, VEGFR, Src, Bcr-Abl
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Autophagy, Cytoskeletal Signaling
Purity
>99.99%
Bioactivity
Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively.
Smiles
Cl.CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cnc4cccnn34)cc2C(F)(F)F)CC1
Molecular Formula
C29H28ClF3N6O
Molecular Weight
569.02
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
500842 200 µg
MYBBP1A, GST-Tag, Recombinant (P160, PAP2, FLJ37886, Myb-Binding Protein 1A) discontinued
Sign In for Pricing
View Details GTR15238877 1 Vial
Lentiviral mouse Prkce shRNA (UAS) - Lentiviral mouse Prkce shRNA (UAS) (25)
Sign In for Pricing
View Details