AMDE-1
Product Specifications
CAS Number
478043-30-0
Target
Autophagy, ATG, AMPK
Related Pathways
Chromatin/Epigenetic, PI3K/Akt/mTOR signaling, Autophagy
Purity
0.9
Bioactivity
AMDE-1 is an autophagy modulator and triggers autophagy in an Atg5-dependent manner. AMDE-1 recruits Atg16 to the pre-autophagosomal site and causes LC3 lipidation.
Smiles
FC(F)(F)C1=NC2=NC(=CC=C2C(=C1)C(F)(F)F)C(C#N)C1=CC(Cl)=CC=C1
Molecular Formula
C18H8ClF6N3
Molecular Weight
415.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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