AlphaSYN-IN-NAB2
Product Specifications
CAS Number
1504588-00-4
Target
Others|||NEDD4-1
Related Pathways
Others|||Metabolism
Purity
0.9956
Bioactivity
AlphaSYN-IN-NAB2, a neuron-protective agent, is a protein encoded by the NAB2 gene. NAB2 effectively and selectively protects a variety of cells from alpha-SYN toxicity. NAB2 promotes endosomal transport dependent on E3 ubiquitin ligase Rsp5/Nedd4. NAB2 identifies a viable molecular node in alpha-SYN biology that corrects multiple aspects of its underlying pathology, including dysfunctional endosomes and endoplasmic reticulum to Golgi vesicles transport. NAB2 is involved in cellular processes such as cell differentiation, apoptosis and stress response, and can be used to study cancer, neurodevelopment and neuronal activity.
Smiles
CC1=C(N2C=3C(=CC(C(NCC4=C(Cl)C=CC=C4)=O)=CC3)N=C2)C=C(C)C=C1
Molecular Formula
C23H20ClN3O
Molecular Weight
389.88
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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