ABC1183
Product Specifications
CAS Number
1042735-18-1
Target
GSK-3|||CDK
Related Pathways
Stem Cells|||PI3K/Akt/mTOR signaling|||Cell Cycle/Checkpoint
Purity
0.9892
Bioactivity
ABC1183 is a novel diaminothiazole that inhibits GSK3?, GSK3? and CDK9. ABC1183 inhibits the growth of a numerous cancer cell lines by decreasing cell survival by inducing G2/M arrest and through altering GSK3, glycogen synthetase, ?-catenin phosphorylation and MCL1 expression, and is orally active.
Smiles
Cc1ccc(Nc2nc(N)c(s2)C(=O)c2ccc(cc2)C#N)cc1
Molecular Formula
C18H14N4OS
Molecular Weight
334.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15356062 1 Vial
Lentiviral human CATIP sgRNA gene knockout kit - Lentiviral human CATIP sgRNA gene knockout kit (plasmid)
Ask
View Details