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ZM 449829

Product Specifications

CAS Number

4452-06-6

Target

EGFR, JAK, Others

Related Pathways

Stem Cells, Angiogenesis, Others, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Chromatin/Epigenetic

Bioactivity

ZM 449829 is an effective, selective inhibitor of Janus tyrosine kinase 3 which binds competitively to the JAK3 ATP site (pIC50: 6.8, 5.0, 4.7, and < 5.0 for JAK3, EGFR, JAK1 and CDK4 respectively) .

Smiles

C=CC(=O)c1ccc2ccccc2c1

Molecular Formula

C13H10O

Molecular Weight

182.222

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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