ZM 449829
Product Specifications
CAS Number
4452-06-6
Target
EGFR, JAK, Others
Related Pathways
Stem Cells, Angiogenesis, Others, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Chromatin/Epigenetic
Bioactivity
ZM 449829 is an effective, selective inhibitor of Janus tyrosine kinase 3 which binds competitively to the JAK3 ATP site (pIC50: 6.8, 5.0, 4.7, and < 5.0 for JAK3, EGFR, JAK1 and CDK4 respectively) .
Smiles
C=CC(=O)c1ccc2ccccc2c1
Molecular Formula
C13H10O
Molecular Weight
182.222
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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