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YM 511

Product Specifications

CAS Number

148869-05-0

Target

Aromatase, Cytochromes P450

Related Pathways

Endocrinology/Hormones, Metabolism

Purity

>99.99%

Bioactivity

YM 511 is a highly specific non-steroidal aromatase inhibitor. YM 511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively (IC50s of 0.4 and 0.12 nM, respectively) . YM 511 slightly inhibits production of other steroid hormones. YM 511 has the potential for suppressing estrogen-dependent action research without affecting serum levels of other steroid hormones.

Smiles

N(CC1=CC=C(Br)C=C1)(C2=CC=C(C#N)C=C2)N3C=NN=C3

Molecular Formula

C16H12BrN5

Molecular Weight

354.2

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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