YM 511
Product Specifications
CAS Number
148869-05-0
Target
Aromatase|||Cytochromes P450
Related Pathways
Endocrinology/Hormones|||Metabolism
Purity
>99.99%
Bioactivity
YM 511 is a highly specific non-steroidal aromatase inhibitor. YM 511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively (IC50s of 0.4 and 0.12 nM, respectively) . YM 511 slightly inhibits production of other steroid hormones. YM 511 has the potential for suppressing estrogen-dependent action research without affecting serum levels of other steroid hormones.
Smiles
N(CC1=CC=C(Br)C=C1)(C2=CC=C(C#N)C=C2)N3C=NN=C3
Molecular Formula
C16H12BrN5
Molecular Weight
354.2
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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