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YIL 781

Product Specifications

CAS Number

875258-85-8

Target

GHSR

Related Pathways

GPCR/G Protein

Purity

0.993

Bioactivity

YIL 781 is a selective ghrelin receptor antagonist (GHS-R1a) (Ki = 17 nM), showing a weak affinity for kinesin receptors (K = 6 μM) . YIL 781 improves glucose homeostasis in vivo and in vitro by blocking ghrelin secretion.

Smiles

O=C1C=2C(N=C(C)N1C[C@@H]3CN(C(C)C)CCC3)=CC=C(OC4=CC=C(F)C=C4)C2

Molecular Formula

C24H28FN3O2

Molecular Weight

409.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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