Xestospongin C
Product Specifications
CAS Number
88903-69-9
Target
Calcium Channel, Apoptosis
Related Pathways
Apoptosis, Membrane transporter/Ion channel, Metabolism
Bioactivity
Xestospongin C ((-) -Xestospongin C) is a selective inositol 1,4,5-trisphosphate receptor (IP3R) inhibitor and also inhibits sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) . It has neuroprotective effects in APP/PS1 AD mice, improving cognitive and pathological deficits associated with Alzheimer's disease.
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[C@@]12([N@@]3CC[C@](O1)(CCCCCC[C@]4([C@@]5(O[C@](CCCCCC[C@]2(CCC3)[H])(CC[N@]5CCC4)[H])[H])[H])[H])[H]
Molecular Formula
C28H50N2O2
Molecular Weight
446.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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