Anxiolytic/nonsedative agent-1
Product Specifications
CAS Number
355022-97-8
Target
GABA Receptor
Related Pathways
Membrane transporter/Ion channel, Neuroscience
Purity
0.9861
Bioactivity
Anxiolytic/nonsedative agent-1 (TCS 1205) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α2β2γ2, α5β3γ2, respectively. Anxiolytic/nonsedative agent-1 shows α2 selective efficacy in vitro and anxioselective effects in vivo.
Smiles
C(C(N[C@H](C)C1=CC=CC=C1)=O)(=O)C=2C=3C(NC2)=CC=C(N(=O)=O)C3
Molecular Formula
C18H15N3O4
Molecular Weight
337.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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