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Anxiolytic/nonsedative agent-1

Product Specifications

CAS Number

355022-97-8

Target

GABA Receptor

Related Pathways

Membrane transporter/Ion channel|||Neuroscience

Purity

0.9861

Bioactivity

Anxiolytic/nonsedative agent-1 (TCS 1205) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for ?1?2?2, ?2?2?2, ?5?3?2, respectively. Anxiolytic/nonsedative agent-1 shows ?2 selective efficacy in vitro and anxioselective effects in vivo.

Smiles

C(C(N[C@H](C)C1=CC=CC=C1)=O)(=O)C=2C=3C(NC2)=CC=C(N(=O)=O)C3

Molecular Formula

C18H15N3O4

Molecular Weight

337.33

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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