TC-N 22A
Product Specifications
CAS Number
1314140-00-5
Target
GluR
Related Pathways
Neuroscience
Purity
0.9995
Bioactivity
TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can cross the blood-brain barrier. EC50 expression of TC-N 22A in BHK cells expressing human mGlu4 was 9 nM. TC-N 22A showed very low activity against mGlu 1, 2, 3, 5, and 7 receptors in excitation and forward allosteric models (EC50 >10 ?M) . TC-N 22A can be used in the study of central nervous system diseases.
Smiles
N(C1=NC=2C=3C(=NNC3)CCCC2S1)C4=CC=CC=N4
Molecular Formula
C14H13N5S
Molecular Weight
283.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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