KW-2449
Product Specifications
CAS Number
1000669-72-6
Target
C-Kit, Aurora Kinase, JAK, Apoptosis, FLT, FGFR, Src, Bcr-Abl
Related Pathways
Cell Cycle/Checkpoint, Angiogenesis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Stem Cells, JAK/STAT signaling, Apoptosis
Purity
0.9989
Bioactivity
KW-2449 is a multiple-targeted inhibitor, mostly for Flt3 (IC50: 6.6 nM), modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.
Smiles
O=C(N1CCNCC1)c1ccc(C=Cc2n[nH]c3ccccc23)cc1
Molecular Formula
C20H20N4O
Molecular Weight
332.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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