SR1664
Product Specifications
CAS Number
1338259-05-4
Target
PPAR
Related Pathways
DNA Damage/DNA Repair, Metabolism
Purity
0.9943
Bioactivity
SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphorylation (IC50 = 80 nM; Ki = 28.67 nM) without exhibiting PPARγ agonist activity.
Smiles
C[C@H](NC(=O)c1ccc2n(Cc3ccc(cc3)-c3ccccc3C(O)=O)c(C)c(C)c2c1)c1ccc(cc1)[N+]([O-])=O
Molecular Formula
C33H29N3O5
Molecular Weight
547.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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