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SR1664

Product Specifications

CAS Number

1338259-05-4

Target

PPAR

Related Pathways

DNA Damage/DNA Repair, Metabolism

Purity

0.9943

Bioactivity

SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphorylation (IC50 = 80 nM; Ki = 28.67 nM) without exhibiting PPARγ agonist activity.

Smiles

C[C@H](NC(=O)c1ccc2n(Cc3ccc(cc3)-c3ccccc3C(O)=O)c(C)c(C)c2c1)c1ccc(cc1)[N+]([O-])=O

Molecular Formula

C33H29N3O5

Molecular Weight

547.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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