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SCH772984 HCl

Product Specifications

Target

ERK

Related Pathways

MAPK

Bioactivity

SCH772984 HCl is a selective inhibitor of ERK1/2 that displays behaviors of both type I and type II kinase inhibitors, with IC50s of 4 and 1 nM, respectively. SCH772984 HCl has nanomolar cellular potency in tumor cells with mutations in BRAF, NRAS, or KRA

Smiles

O=C(NC1=CC2=C(NN=C2C3=CC=NC=C3)C=C1)[C@H]4CN(CC(N5CCN(C6=CC=C(C7=NC=CC=N7)C=C6)CC5)=O)CC4.[H]Cl

Molecular Formula

C33H34ClN9O2

Molecular Weight

624.14

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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