Neratinib
Product Specifications
CAS Number
698387-09-6
Target
EGFR, HER
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling
Purity
>99.99%
Bioactivity
Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.
Smiles
N(C=1C2=C(C=C(OCC)C(NC(/C=C/CN(C)C)=O)=C2)N=CC1C#N)C3=CC(Cl)=C(OCC4=CC=CC=N4)C=C3
Molecular Formula
C30H29ClN6O3
Molecular Weight
557.04
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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