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Neratinib

Product Specifications

CAS Number

698387-09-6

Target

EGFR, HER

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling

Purity

>99.99%

Bioactivity

Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.

Smiles

N(C=1C2=C(C=C(OCC)C(NC(/C=C/CN(C)C)=O)=C2)N=CC1C#N)C3=CC(Cl)=C(OCC4=CC=CC=N4)C=C3

Molecular Formula

C30H29ClN6O3

Molecular Weight

557.04

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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