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PPY A

Product Specifications

CAS Number

875634-01-8

Target

Bcr-Abl

Related Pathways

Angiogenesis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors

Purity

0.9877

Bioactivity

PPY A is a potent inhibitor of T315l mutant and wild-type Abl kinase (IC50 of 9 and 20 nM, respectively) .PPY A also inhibits the growth of Bcr-Abl T315l mutant or wild-type Bcr-Abl genetically transformed cells.

Smiles

O=C(C1=CN=CC(=C1)C2=CN=C3NC=C(C=4C=CC=CC4OC)C3=C2)N(C)C

Molecular Formula

C22H20N4O2

Molecular Weight

372.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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