Posaconazole hydrate
Product Specifications
CAS Number
1198769-38-8
Target
Others, Antifungal, Parasite
Related Pathways
Microbiology/Virology, Others
Bioactivity
Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. Posaconazole is a sterol C14ɑ demethylase inhibitor (IC50: 0.25 nM) . Posaconazole strongly inhibits 14-alpha demethylase, a cytochrome P450-dependent enzyme.
Smiles
C([C@@]1(C[C@H](COC2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)N5C(=O)N([C@H]([C@H](C)O)CC)N=C5)CO1)C6=C(F)C=C(F)C=C6)N7C=NC=N7.O
Molecular Formula
C37H44F2N8O5
Molecular Weight
718.79
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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