PD-161570
Product Specifications
CAS Number
192705-80-9
Target
TGF-beta/Smad, Src, PDGFR, FGFR, EGFR
Related Pathways
Stem Cells, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis
Purity
0.9992
Bioactivity
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. It also inhibits the PDGFR, EGFR, and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, and 44 nM, respectively.
Smiles
CCN(CC)CCCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1c(Cl)cccc1Cl
Molecular Formula
C26H35Cl2N7O
Molecular Weight
532.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
A03502-2-Biotin 100 µg/Vial
Anti-LMO2 Antibody Picoband® (Biotine Conjugate)
Sign In for Pricing
View Details 
MBS1032787-01 0.02 mg (E-Coli)
Recombinant Geobacillus stearothermophilus N-acyl-L-amino acid amidohydrolase (amaA)
Sign In for Pricing
View Details MBS1032787-02 0.02 mg (Yeast)
Recombinant Geobacillus stearothermophilus N-acyl-L-amino acid amidohydrolase (amaA)
Sign In for Pricing
View Details MBS1032787-03 0.1 mg (E-Coli)
Recombinant Geobacillus stearothermophilus N-acyl-L-amino acid amidohydrolase (amaA)
Sign In for Pricing
View Details