PD-161570
Product Specifications
CAS Number
192705-80-9
Target
TGF-beta/Smad|||Src|||PDGFR|||FGFR|||EGFR
Related Pathways
Stem Cells|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis
Purity
0.9992
Bioactivity
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. It also inhibits the PDGFR, EGFR, and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, and 44 nM, respectively.
Smiles
CCN(CC)CCCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1c(Cl)cccc1Cl
Molecular Formula
C26H35Cl2N7O
Molecular Weight
532.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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