PD-161570

Product Specifications

CAS Number

192705-80-9

Target

TGF-beta/Smad|||Src|||PDGFR|||FGFR|||EGFR

Related Pathways

Stem Cells|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis

Purity

0.9992

Bioactivity

PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. It also inhibits the PDGFR, EGFR, and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, and 44 nM, respectively.

Smiles

CCN(CC)CCCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1c(Cl)cccc1Cl

Molecular Formula

C26H35Cl2N7O

Molecular Weight

532.51

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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