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M-Chlorophenylbiguanide hydrochloride

Product Specifications

CAS Number

77923

Target

5-HT Receptor

Related Pathways

GPCR/G Protein|||Neuroscience

Purity

0.9989

Bioactivity

M-Chlorophenylbiguanide hydrochloride is a 5-HT3 receptor agonist. m-Chlorophenylbiguanide hydrochloride selectively binds 5-HT3 (Ki: 0.002 µM) over 5-HT1A (Ki: 10 µM) and 5-HT2 (Ki: 10 µM) receptors but also binds to high and low affinity sites on the dopamine transporter (DAT; IC50s: 0.4 and 34.8 µM, respectively, in rat caudate putamen synaptosomal membranes) .

Smiles

Cl.NC(N)=NC(=N)NC1=CC(Cl)=CC=C1

Molecular Formula

C8H11Cl2N5

Molecular Weight

248.11

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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