LY 456236 hydrochloride
Product Specifications
CAS Number
338736-46-2
Target
EGFR, GluR
Related Pathways
JAK/STAT signaling, Neuroscience, Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9995
Bioactivity
LY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of 143 nM. LY456236 has selective, non-competitive and oral activity, and can inhibit the hydrolysis of inositol phosphate with IC50 of 0.145 μM. LY 456236 hydrochloride inhibited EGFR with IC50 of 0.91 μM.
Smiles
Cl.COc1ccc(Nc2ncnc3ccc(OC)cc23)cc1
Molecular Formula
C16H16ClN3O2
Molecular Weight
317.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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