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LY 456236 hydrochloride

Product Specifications

CAS Number

338736-46-2

Target

EGFR, GluR

Related Pathways

JAK/STAT signaling, Neuroscience, Angiogenesis, Tyrosine Kinase/Adaptors

Purity

0.9995

Bioactivity

LY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of 143 nM. LY456236 has selective, non-competitive and oral activity, and can inhibit the hydrolysis of inositol phosphate with IC50 of 0.145 μM. LY 456236 hydrochloride inhibited EGFR with IC50 of 0.91 μM.

Smiles

Cl.COc1ccc(Nc2ncnc3ccc(OC)cc23)cc1

Molecular Formula

C16H16ClN3O2

Molecular Weight

317.77

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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