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L748337

Product Specifications

CAS Number

244192-94-7

Target

Adrenergic Receptor

Related Pathways

GPCR/G Protein, Neuroscience

Purity

>99.99%

Bioactivity

L748337 is a competitive and potent β3-adrenoceptor antagonist that inhibits the action of β3-, β2-, and β1-adrenoceptors, activates MAPK signaling, promotes phosphorylation of Erk1/2, and inhibits the protective effects of CL316243, and is used in the study of disorders caused by abnormalities of the β3-adrenoceptors.

Smiles

CC(=O)NCc1cccc(OC[C@@H](O)CNCCc2ccc(NS(=O)(=O)c3ccccc3)cc2)c1

Molecular Formula

C26H31N3O5S

Molecular Weight

497.61

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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