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N6-Benzoyl-2'-fluoro-2'-deoxyarabinoadenosine

N6-Benzoyl-2'-fluoro-2'-deoxyarabinoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) [1].

Product Specifications

CAS Number

[144924-99-2]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n6-benzoyl-2-fluoro-2-deoxyarabinoadenosine.html

Solubility

10 mM in DMSO

Smiles

OC[C@@H]1[C@@H](O)[C@H](F)[C@H](N2C3=NC=NC(NC(C4=CC=CC=C4)=O)=C3N=C2)O1

Molecular Formula

C17H16FN5O4

Molecular Weight

373.34

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26 (6) :1490-1500.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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