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L-365260

Product Specifications

CAS Number

118101-09-0

Target

Cholecystokinin Receptor

Related Pathways

GPCR/G Protein

Purity

0.9975

Bioactivity

L-365260 is an orally available, selective and potent nonpeptide gastrin and cerebral cholecystokinin receptor (CCK-B) antagonist.L-365260 inhibits CCK-8S-induced increase in [Ca2+]i, blocks stress-induced hypersensitivity in viscera, and blocks the anti-exploratory effect of CCK-4.L-365260 has been used in the study of neurological Ojibwa and endocrine diseases.

Smiles

CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2cccc(C)c2)C1=O)c1ccccc1

Molecular Formula

C24H22N4O2

Molecular Weight

398.46

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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