L-365260
Product Specifications
CAS Number
118101-09-0
Target
Cholecystokinin Receptor
Related Pathways
GPCR/G Protein
Purity
0.9975
Bioactivity
L-365260 is an orally available, selective and potent nonpeptide gastrin and cerebral cholecystokinin receptor (CCK-B) antagonist.L-365260 inhibits CCK-8S-induced increase in [Ca2+]i, blocks stress-induced hypersensitivity in viscera, and blocks the anti-exploratory effect of CCK-4.L-365260 has been used in the study of neurological Ojibwa and endocrine diseases.
Smiles
CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2cccc(C)c2)C1=O)c1ccccc1
Molecular Formula
C24H22N4O2
Molecular Weight
398.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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