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Motesanib

Product Specifications

CAS Number

453562-69-1

Target

VEGFR, c-Kit

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors

Purity

0.9909

Bioactivity

Motesanib (AMG 706) is an orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-derived growth factor (PDGFR), Kit, and Ret receptors, thereby inhibiting angiogenesis and cellular proliferation.

Smiles

CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc12

Molecular Formula

C22H23N5O

Molecular Weight

373.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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