Motesanib
Product Specifications
CAS Number
453562-69-1
Target
VEGFR, c-Kit
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9909
Bioactivity
Motesanib (AMG 706) is an orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-derived growth factor (PDGFR), Kit, and Ret receptors, thereby inhibiting angiogenesis and cellular proliferation.
Smiles
CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc12
Molecular Formula
C22H23N5O
Molecular Weight
373.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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