PIK-75 hydrochloride
Product Specifications
CAS Number
372196-77-5
Target
PI3K|||Apoptosis|||DNA-PK
Related Pathways
PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair|||Apoptosis
Purity
0.98
Bioactivity
PIK-75 hydrochloride (PIK-75 HCl) is a p110? inhibitor with IC50 of 5.8 nM (200-fold more potently than p110?), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.
Smiles
Cl.CN(N=Cc1cnc2ccc(Br)cn12)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O
Molecular Formula
C16H14BrN5O4S·HCl
Molecular Weight
488.74
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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