GSA-10
Product Specifications
CAS Number
300833-95-8
Target
Hedgehog/Smoothened|||Smo
Related Pathways
GPCR/G Protein|||Stem Cells
Purity
0.9971
Bioactivity
GSA-10 is a potent Smoothened (Smo) receptor agonist with an EC50 of 1.2 ?M. It acts on Smo to promote the differentiation of pluripotent mesenchymal stem cells into osteoblasts. It also mediates Hedgehog (Hh) signaling, which may have research implications for regenerative medicine in cancer diseases.
Smiles
CCCCCCn1c2ccccc2c(O)c(C(=O)Nc2ccc(cc2)C(=O)OCCC)c1=O
Molecular Formula
C26H30N2O5
Molecular Weight
450.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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