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GSA-10

Product Specifications

CAS Number

300833-95-8

Target

Hedgehog/Smoothened|||Smo

Related Pathways

GPCR/G Protein|||Stem Cells

Purity

0.9971

Bioactivity

GSA-10 is a potent Smoothened (Smo) receptor agonist with an EC50 of 1.2 ?M. It acts on Smo to promote the differentiation of pluripotent mesenchymal stem cells into osteoblasts. It also mediates Hedgehog (Hh) signaling, which may have research implications for regenerative medicine in cancer diseases.

Smiles

CCCCCCn1c2ccccc2c(O)c(C(=O)Nc2ccc(cc2)C(=O)OCCC)c1=O

Molecular Formula

C26H30N2O5

Molecular Weight

450.53

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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