Pruvanserin hydrochloride
Product Specifications
CAS Number
443144-27-2
Target
5-HT Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Purity
0.996
Bioactivity
Pruvanserin hydrochloride (EMD 281014 HCl) is an inverse and selective 5-HT2A receptor antagonist with IC50 values of 0.35 nM and 1 nM for human and rat 5-HT2A receptors, respectively. Pruvanserin hydrochloride inhibits GTP-gamma-S accumulation and alleviates tactile allodynia in diabetic rats, making it suitable for studies on Parkinson's disease, insomnia, and schizophrenia.
Smiles
Cl.N#CC1=CNC2=C1C=CC=C2C(=O)N3CCN(CCC4=CC=C(F)C=C4)CC3
Molecular Formula
C22H22ClFN4O
Molecular Weight
412.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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