TLR3-IN-1
Product Specifications
CAS Number
1279713-77-7
Target
TLR
Related Pathways
Immunology/Inflammation
Purity
0.9856
Bioactivity
TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor (IC50: 3.44 μM in RAW 264.7 cells) . It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the production of TNF-α and IL-1β in whole cells.
Smiles
OC(=O)[C@@H](Cc1ccccc1)NC(=O)c1sc2cc(F)ccc2c1Cl
Molecular Formula
C18H13ClFNO3S
Molecular Weight
377.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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