Oxysophocarpine
Oxysophocarpine is an alkaloid extracted from Sophora alopecuroides. Oxysophocarpine has neuroprotective and anti-nociceptive effects on the central and peripheral nervous systems[1]. Oxysophocarpine inhibits the growth and metastasis of oral squamous cell carcinoma (OSCC) [2].
Product Specifications
CAS Number
[26904-64-3]
UNSPSC
12352005
Hazard Statement
H302
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/oxysophocarpine.html
Purity
99.59
Solubility
DMSO : 36.67 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
Smiles
O=C1C=CC[C@]2([H])[C@@]3([H])CCC[N@@+]4([O-])[C@@]3([H])[C@](CCC4)([H])CN21
Molecular Formula
C15H22N2O2
Molecular Weight
262.35
Precautions
H302
References & Citations
[1] Xu T, et al. Oxysophocarpine induces anti-nociception and increases the expression of GABAAα1 receptors in mice.Mol Med Rep. 2013 Jun;7 (6) :1819-25.|[2]Liu, R., Peng, J., Wang, H., et al. Oxysophocarpine retards the growth and metastasis of oral squamous cell carcinoma by targeting the Nrf2/HO-1 axis. Cell Physiol. Biochem. 49 (5), 1717-1733 (2018) .
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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