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CFM 4

Product Specifications

CAS Number

331458-02-7

Target

APC/C, Apoptosis

Related Pathways

Cell Cycle/Checkpoint, Apoptosis

Purity

0.9882

Bioactivity

CFM 4 is a potent small molecule CARP-1/APC-2 antagonist that prevents CARP-1 from binding to APC-2, contributes to G2M cell cycle arrest, and induces apoptosis, with an IC50 in the range of 10-15 μM.CFM 4 inhibits the growth of drug-resistant human breast cancer cells.

Smiles

O=C1C2(C=3C(N1CC4=C(Cl)C=CC=C4)=CC=CC3)SC(=NN2)C5=CC=CC=C5

Molecular Formula

C22H16ClN3OS

Molecular Weight

405.9

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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