CFM 4
Product Specifications
CAS Number
331458-02-7
Target
APC/C, Apoptosis
Related Pathways
Cell Cycle/Checkpoint, Apoptosis
Purity
0.9882
Bioactivity
CFM 4 is a potent small molecule CARP-1/APC-2 antagonist that prevents CARP-1 from binding to APC-2, contributes to G2M cell cycle arrest, and induces apoptosis, with an IC50 in the range of 10-15 μM.CFM 4 inhibits the growth of drug-resistant human breast cancer cells.
Smiles
O=C1C2(C=3C(N1CC4=C(Cl)C=CC=C4)=CC=CC3)SC(=NN2)C5=CC=CC=C5
Molecular Formula
C22H16ClN3OS
Molecular Weight
405.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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