CDK8/19-IN-51
Product Specifications
CAS Number
1860885-61-5
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
>99.99%
Bioactivity
CDK8/19-IN-51 is an orally active and highly effective dual inhibitor of CDK8 and CDK19, with anticancer activity. Its IC50 values for CDK8 and CDK19 are 5.1 nM and 5.6 nM, respectively. It is used in studies of colorectal and gastric cancers.
Smiles
O=C(C1=NC2=C(C=NC(N)=C2C=C1)C3=CC=C(C=C3)C=4C=NN(C4)C)N5CC(OC)C5
Molecular Formula
C23H22N6O2
Molecular Weight
414.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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