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KenPaullone

Product Specifications

CAS Number

142273-20-9

Target

GSK-3, CDK

Related Pathways

PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint, Stem Cells

Purity

0.9899

Bioactivity

KenPaullone (9-Bromopaullone), a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell differentiation. Kenpaullone promotes iTreg cell differentiation through increased and prolonged transcription of foxp3 gene by enhancing TGFβ-Smad3 signaling pathway.

Smiles

Brc1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1

Molecular Formula

C16H11BrN2O

Molecular Weight

327.18

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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