1,2,3,4,5,6-Hexabromocyclohexane
Product Specifications
CAS Number
1837-91-8
Target
JAK, Others
Related Pathways
Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Angiogenesis, Others, Stem Cells, JAK/STAT signaling
Bioactivity
The compound effectively and directly inhibits JAK2 tyrosine kinase autophosphorylation and specifically inhibits ligand-dependent JAK2 activation. It has no cytotoxicity at 100 μM. A 16-hour treatment with compound (1 μM) decreases JAK2 tyrosine autophosphorylation levels to ~ 50% while 50 μM eliminates nearly all JAK2 activity.
Smiles
BrC1C(Br)C(Br)C(Br)C(Br)C1Br
Molecular Formula
C6H6Br6
Molecular Weight
557.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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