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YKL-5-124

Product Specifications

CAS Number

1957203-01-8

Target

CDK

Related Pathways

Cell Cycle/Checkpoint

Purity

0.995

Bioactivity

YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displays biochemical and cellular selectivity for CDK7 over CDK12/13.

Smiles

CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3ccc(NC(=O)C=C)cc3)n[nH]c2C1(C)C)c1ccccc1

Molecular Formula

C28H33N7O3

Molecular Weight

515.61

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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